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As regulatory agencies tighten restrictions on high-GWP (Global Warming Potential) refrigerants, HVAC/R professionals are racing to find eco-friendly, efficient, and compatible replacements for older refrigerants like R-404A, R-507A, and R-407 series blends. Enter R-449A (XP40) — the next-generation refrigerant engineered to meet modern environmental standards without sacrificing performance.
In this in-depth guide, we’ll explore everything you need to know about R-449A (XP40) 25 lb Cylinder MADE IN USA 404/507/407 Replacement, available now at RoyalRefrigerants.com. We’ll break down its chemical structure, performance capabilities, regulatory compliance, and real-world applications. Whether you're a facility manager, service contractor, or business owner, this refrigerant is built for your future.

What is R-449A (XP40)?
R-449A, also known by its brand name XP40, is a non-ozone-depleting, HFO/HFC blend refrigerant developed by Chemours as part of the Opteon™ line. It is designed as a drop-in replacement for high-GWP refrigerants commonly used in low- and medium-temperature commercial refrigeration systems.
📦 Product Highlights:
✔ Size: 25 lb factory-sealed cylinder
✔ Origin: Made in USA
✔ Replacement For: R-404A, R-507A, R-407A/F
✔ Ideal For: Supermarkets, cold storage, food service, and logistics facilities
Why Replace R-404A, R-507, or R-407?
🔍 The Problem:
Refrigerants like R-404A and R-507A have long been industry staples. But their high GWP values — over 3900 — have made them targets for phase-out programs under the EPA’s SNAP Program, F-Gas Regulations, and international agreements like the Kigali Amendment.
These refrigerants are:
✔ Expensive to source
✔ Restricted or banned in many states and countries
✔ Harmful to the environment
✅ The Solution: R-449A
With a GWP of ~1397 (over 60% lower than R-404A), R-449A is an EPA-approved and ASHRAE-recognized alternative that reduces environmental impact while maintaining performance.
R-449A Performance Benefits: Efficiency Meets Compliance
⚙️ Comparable Cooling Performance
R-449A offers nearly 98% of R-404A’s cooling capacity, making it ideal for retrofitting existing systems without major hardware changes.
💡 Lower Discharge Temperature
This reduces compressor wear and increases overall system longevity — a win for service technicians and equipment owners alike.
⚡️ Improved Energy Efficiency
Many facilities switching to R-449A report 8–12% energy savings, especially in medium-temp systems.
🌱 Environmentally Superior
✔ Zero ODP (Ozone Depletion Potential)
✔ GWP of 1397 — significantly better than legacy refrigerants
✔ SNAP-Approved for new and retrofit applications
Technical Specifications of R-449A (XP40)
Property |
Value |
Chemical Composition |
R-32 / R-125 / R-134a / R-1234yf |
ASHRAE Classification |
A1 (Non-toxic, non-flammable) |
GWP |
~1397 |
ODP |
0 |
Oil Type |
POE (Polyolester) |
Glide |
~7°F |
Operating Range |
-20°F to +50°F Evap. Temp |
Compatibility |
Retrofit & new systems |
Made in the USA: Why It Matters
Purchasing refrigerant manufactured in the USA offers several key benefits:
🇺🇸 Higher Quality Assurance
Products meet stringent American manufacturing standards, ensuring consistency and safety.
📦 Faster Domestic Shipping
Royal Refrigerants offers same business day shipping, reducing downtime for service techs and facilities.
🛡️ Better Warranty & Support
Products are backed by U.S.-based support teams for faster resolution and reliable service.
How to Retrofit R-404A or R-507 to R-449A
One of the best features of R-449A is its ease of retrofitting into existing systems. Here's a simplified step-by-step process:
1. System Evaluation
Check equipment compatibility, including oil type (must be POE), line set integrity, and capacity demands.
2. Refrigerant Recovery
Fully remove the existing charge (R-404A or R-507) and dispose according to EPA guidelines.
3. Component Check & Oil
Verify seals, gaskets, and valves for material compatibility. Replace if needed. No oil change if POE is already used.
4. Evacuation & Leak Test
Vacuum the system and check for leaks with nitrogen pressure test.
5. Charge with R-449A
Always charge as a liquid to ensure blend accuracy. Use factory-sealed 25 lb cylinder.
6. Label the System
Clearly mark the new refrigerant and key specs for future service.
Why Choose a 25 lb Cylinder?
The 25 lb size is the gold standard for small- to mid-size applications and field service work.
✔ Portable & Convenient
Lightweight and easy to transport for technicians.
✔ Ideal for Retrofits
Provides enough charge for several average-sized systems.
✔ Minimizes Waste
Use only what you need — great for cost control and environmental responsibility.
Buy from Royal Refrigerants: The Trusted Source
✅ EPA-Certified Sales
We comply with EPA regulations, requiring certification from all refrigerant buyers.
✅ Factory Sealed, Tamper-Proof
Every cylinder is leak-tested and sealed at the factory.
✅ Same Business Day Shipping
Orders placed by 2 PM EST ship that same day — reducing downtime and project delays.
✅ Made in the USA Quality
You get dependable, American-made refrigerant that performs every time.
Customer Testimonials
“I switched my restaurant’s entire cold storage to R-449A using Royal’s 25 lb cylinders. The performance is solid, and energy use dropped noticeably.”
— Jason R., Restaurant Owner, NY
“Same day shipping was a game-changer. I had the cylinder the next morning and got my client’s system up by noon.”
— Lisa M., HVAC Technician, TX
Conclusion: The Smart Choice for Refrigeration Professionals
The transition away from high-GWP refrigerants is already underway, and businesses that fail to act will face rising costs, compliance risks, and performance issues. With R-449A (XP40) 25 lb Cylinder MADE IN USA 404/507/407 Replacement, you get a refrigerant that checks every box:
✅ Environmentally responsible
✅ Energy-efficient
✅ Compatible with existing systems
✅ Readily available and domestically manufactured
For field techs, facility managers, and HVAC contractors, R-449A XP40 offers peace of mind and performance in a convenient, trusted package — and Royal Refrigerants is the supplier that gets it to you fast and reliably.
🚀 Order Now and Upgrade with Confidence
🔗 Buy R-449A (XP40) 25 lb Cylinder – Made in USA – Royal Refrigerants