This product can no longer be sold/purchased in California or New York

$328.00
Keep legacy HVAC and refrigeration equipment in service with this 25 lb R-422B refrigerant cylinder, supplied sealed for professional service and approved retrofit applications. R-422B is an HFC refrigerant blend...

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Keep legacy HVAC and refrigeration equipment in service with this 25 lb R-422B refrigerant cylinder, supplied sealed for professional service and approved retrofit applications.

R-422B is an HFC refrigerant blend commonly used as an alternative to R-22 in certain existing air-conditioning and refrigeration systems. It is especially relevant for HVAC-R contractors, service technicians, facility maintenance teams, and commercial buyers working with compatible legacy equipment.

This high-purity, American-branded R-422B 25 lb refrigerant cylinder provides a practical quantity for planned retrofit work, maintenance, and service calls.

R-422B should only be used where equipment requirements and an approved retrofit procedure support its use. Always review the equipment manufacturer’s specifications and applicable technical guidance before converting or charging a system.

R-422B Refrigerant Product Details

  • Refrigerant: R-422B

  • Cylinder size: 25 lb

  • Product positioning: High-purity, American-branded refrigerant

  • Packaging: Sealed cylinder

  • Refrigerant type: HFC blend

  • Composition: 55% R-125, 42% R-134a, 3% R-600a

  • Safety classification: A1

  • Ozone depletion potential: 0

  • EPA GWP reference value: 2,530

  • Common application: Approved retrofit and service applications involving compatible R-22 equipment

  • Purchase requirements: Applicable EPA refrigerant sales restrictions apply

R-422B Refrigerant for Existing R-22 Systems

R-422B was developed for use in certain systems that historically operated with R-22.

Depending on equipment design and retrofit requirements, R-422B may be considered for applications such as:

  • Residential air-conditioning equipment

  • Light-commercial air-conditioning systems

  • Packaged rooftop units

  • Certain heat-pump applications

  • Commercial refrigeration equipment

  • Remote condensing systems

  • Certain refrigerated transport systems

  • Other compatible direct-expansion R-22 equipment

Application alone does not establish compatibility.

Before selecting R-422B, technicians should confirm that the equipment and intended end use support the refrigerant and review the applicable retrofit procedure.

Is R-422B a Replacement for R-22?

R-422B can be used as an R-22 replacement refrigerant in certain approved retrofit applications, but it should not be presented as a universal drop-in replacement.

A refrigerant retrofit involves more than removing one refrigerant and adding another.

Technicians should evaluate:

  • Equipment manufacturer guidance

  • Compressor compatibility

  • Lubricant condition and requirements

  • Metering device sizing and operation

  • Seals and elastomers

  • Refrigerant charge

  • Operating pressures and temperatures

  • System controls

  • Overall equipment condition

The existing R-22 charge should be properly recovered before R-422B is introduced.

Do not mix R-422B with R-22 or another refrigerant.

R-422B Composition

R-422B is a blended refrigerant consisting of:

  • 55% R-125

  • 42% R-134a

  • 3% R-600a

The blend has zero ozone depletion potential and carries an A1 safety classification.

Because R-422B is a refrigerant blend rather than a single-component refrigerant, HVAC-R professionals should use appropriate R-422B pressure-temperature information and follow the correct charging procedures for the product.

Always use current supplier technical data and professional service procedures when evaluating system pressures and temperatures.

R-422B and Lubricant Compatibility

R-422B has historically been used in retrofit applications involving several lubricant types found in legacy R-22 equipment.

Depending on the specific equipment and retrofit procedure, existing mineral oil, alkylbenzene, or POE lubricant may be compatible with the application.

However, technicians should not assume that every R-22 system can be converted without evaluating lubricant condition or oil return.

An approved retrofit may require:

  • Oil analysis

  • Lubricant adjustment

  • Filter-drier replacement

  • Seal or O-ring replacement

  • Metering-device evaluation

  • Additional system adjustments

Oil return and overall system performance depend on equipment design, piping configuration, operating conditions, and compressor requirements.

Is R-422B the Same as NU-22B?

R-422B is the standardized refrigerant designation.

NU-22B is a trade name that has been used for an R-422B product. Other R-422B products may be sold under different brands.

This Royal Refrigerants product is offered as a high-purity American-branded R-422B refrigerant cylinder. Buyers specifically requiring a particular trade name or manufacturer should verify the cylinder branding before purchasing.

The refrigerant designation, equipment compatibility, and approved retrofit procedure are more important than relying on a trade name alone.

25 lb R-422B Refrigerant Cylinder

The 25 lb R-422B cylinder provides a practical quantity for professional HVAC-R contractors and maintenance teams servicing multiple compatible systems.

Before using the cylinder, verify:

  • Refrigerant designation

  • Cylinder condition

  • Product label

  • Safety Data Sheet

  • Service connection

  • Equipment compatibility

  • Applicable retrofit instructions

Store, transport, and handle the refrigerant according to product labeling, applicable regulations, and professional refrigerant-handling requirements.

Is R-422B Still Used?

Yes. R-422B remains relevant for maintaining and retrofitting certain existing systems originally designed for R-22.

R-22 production and import for newly manufactured refrigerant have ended in the United States, but many R-22 systems remain in service.

For some equipment, an approved R-422B retrofit may provide a way to continue operating an otherwise serviceable system without immediately replacing the entire HVAC or refrigeration system.

The appropriate decision depends on equipment condition, system design, manufacturer guidance, local regulations, refrigerant availability, and the economics of continued operation.

R-422B Environmental Considerations

R-422B has zero ozone depletion potential, which distinguishes it from R-22.

However, R-422B is still a high-GWP HFC refrigerant. It should therefore not be described as low-GWP, environmentally friendly, or a next-generation refrigerant.

Its strongest role in today’s market is as a service and retrofit option for certain existing equipment.

Technicians and equipment owners should consider current regulations and manufacturer recommendations when deciding whether to retrofit an existing system or replace the equipment with a newer lower-GWP system.

R-422B Safety and Professional Handling

R-422B carries an A1 safety classification, meaning it is classified as lower toxicity and does not propagate flame under the applicable refrigerant safety standard.

It is still a liquefied gas stored under pressure and requires professional handling.

HVAC-R technicians should follow:

  • The product Safety Data Sheet

  • Equipment manufacturer instructions

  • Approved retrofit guidance

  • Proper refrigerant recovery procedures

  • Applicable federal, state, and local regulations

  • Cylinder storage and transportation requirements

  • Appropriate personal protective equipment requirements

Use professional charging, recovery, and service equipment suitable for the application.

Do not intentionally vent refrigerant into the atmosphere.

Who Can Purchase R-422B Refrigerant?

Federal refrigerant sales restrictions apply to R-422B intended for stationary air-conditioning and refrigeration equipment.

Purchasers generally must be EPA Section 608 certified technicians, qualifying employers or authorized representatives of certified technicians, qualifying resellers, or other purchasers permitted under applicable EPA rules.

Section 609 certification applies to motor-vehicle air-conditioning applications and does not by itself authorize the purchase of refrigerant intended for stationary HVAC equipment.

State and local restrictions may also apply.

Buy R-422B 25 lb Refrigerant Online

Royal Refrigerants supplies HVAC contractors, refrigeration professionals, mechanical contractors, facility teams, and commercial buyers with refrigerants for a broad range of service applications.

If you are looking for R-422B refrigerant for sale, this 25 lb high-purity sealed cylinder provides an option for qualified professionals servicing or retrofitting compatible equipment.

Royal Refrigerants combines decades of refrigerant-industry experience with competitive pricing, knowledgeable support, commercial purchasing options, and dependable fulfillment where sale and delivery are permitted.

We offer FREE continental US shipping. Most orders are shipped same day or next day by Hazmat Ground. You will receive an email notification with tracking when your order is shipped.
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