You have no items in your shopping cart.
Everything You Need to Know About MO99 Refrigerant Cost for HVAC and Automotive Applications
As older refrigerants like R22 are phased out due to their environmental impact, technicians and system owners are turning to modern, efficient, and eco-friendly alternatives. One of the most popular choices is MO99 (R438A) — a direct replacement for R22 in many HVAC and refrigeration systems. It offers excellent performance, easy retrofitting, and compliance with global environmental standards.
If you’re considering switching to MO99 or want to understand its pricing, this article covers everything you need to know about MO99 refrigerant cost and its role in HVAC and automotive applications.
What Is MO99 Refrigerant?
MO99, also known as R438A, is a hydrofluorocarbon (HFC) blend designed as a direct replacement for R22 in existing air conditioning and refrigeration systems. Developed by Chemours, MO99 allows technicians to retrofit older systems without significant equipment modifications, saving time and money.
MO99 has zero ozone depletion potential (ODP) and a global warming potential (GWP) of around 2265, significantly lower than R22. It is compatible with traditional mineral oil and alkylbenzene lubricants, making retrofitting straightforward.
Why Choose MO99 as an R22 Replacement?
✅ Drop-in Solution: MO99 can be used in most existing R22 systems with minimal changes.
🌱 Environmentally Friendly: Zero ODP and lower GWP make it compliant with environmental regulations.
⚙️ Efficient Performance: Delivers cooling performance comparable to R22.
💰 Cost-Effective Retrofit: No need to replace the entire system, saving on expensive equipment upgrades.
🧰 Easy Maintenance: Compatible with existing oils and components, simplifying the retrofit process.
Cost Factors for MO99 Refrigerant
The cost of MO99 varies based on several key factors:
- 🏭 Quantity Purchased: Bulk purchases are more cost-effective per pound.
- 📍 Location and Supplier: Prices may vary depending on your region and distributor.
- 📦 Market Demand and Availability: Seasonal demand and global supply chain conditions can affect pricing.
- 🧰 System Size and Type: The amount required depends on the size of your HVAC or refrigeration system.
- 📆 Regulatory Changes: Market prices may fluctuate as older refrigerants are phased out and demand for replacements increases.
Average MO99 Refrigerant Price
As of 2025, the average cost of MO99 refrigerant ranges from:
- 💨 $10 – $20 per pound for small-scale retail purchases.
- 🏭 $250 – $400 per 25 lb cylinder when bought in bulk.
Prices can fluctuate based on supplier, region, and global refrigerant market trends. While MO99 is slightly more expensive than older refrigerants, it’s far more cost-effective than replacing an entire R22 system.

Applications of MO99 in HVAC and Automotive Systems
HVAC Systems
MO99 is widely used as a direct replacement for R22 in residential, commercial, and industrial air conditioning systems. It offers similar cooling performance without major modifications, making it ideal for retrofitting older units.
Refrigeration Systems
It’s commonly used in supermarket refrigeration, cold storage, and commercial freezers, where maintaining precise temperature control is essential.
Automotive Applications
While MO99 is primarily designed for stationary systems, it can also be used in some automotive A/C retrofits with proper system adjustments and professional guidance.
Pros and Cons of MO99 Refrigerant
Pros:
- Direct drop-in replacement for R22
- Zero ODP and reduced GWP
- Minimal system modification required
- Cost-effective retrofit solution
- Compatible with existing lubricants
Cons:
- Slightly higher cost than older refrigerants
- Performance may vary slightly depending on system type
- Limited use in some specialized automotive systems
Tips for Buying MO99 Refrigerant
- 📦 Buy in Bulk: Larger cylinders offer better value per pound.
- 🧰 Verify Supplier Certification: Always purchase from certified distributors to ensure product quality.
- 🧪 Check Compatibility: Consult a qualified HVAC technician before retrofitting your system.
- 📜 Stay Updated on Regulations: Monitor local refrigerant regulations to ensure compliance.
Conclusion
MO99 (R438A) is one of the most effective and environmentally responsible alternatives to R22, offering excellent performance, minimal retrofit requirements, and long-term cost savings. While its upfront cost may be slightly higher than older refrigerants, the benefits of compliance, efficiency, and ease of use make MO99 a smart investment for both HVAC and automotive applications.
As the industry continues to move toward low-impact refrigerants, MO99 stands out as a practical, future-proof solution for technicians and system owners alike.